I thought the settings by the Control Panel is saved in the EEPROM of Orpheus when it is powered off, but I was (partially) wrong in my understanding.
According to the manual,
http://www.prismsound.com/music_recording/products_subs/orpheus/online_manual/index.html, (Contents -> Orpheus hardware -> Stand-alone operation):
When the unit is re-powered, and detects that no FireWire connection is active, it reloads the settings which were previously stored.